Contact Us

Opening hours: Monday to Friday: 8:00am to 5:00pm, Saturday: 8:30am to 12:30pm

SIGN UP
SIGN UP

Tag: medical

Posted on

Diabetic ketoacidosis in children equals to hypertension

Cr. Rene Bernal

Source from MIMS.com

Study has found that for children with diabetic ketoacidosis (DKA), hypertension is a common phenomenon.

Researchers gathered 1,258 patients who had sufficient haemodynamic data for the present analysis while using data from the Paediatric Emergency Care Applied Research Network. Out of these, 12.2 percent had documented hypertension at presentation.

In under 2 hours, hypertension were resolved quickly in 36 children and for 118 episodes, hypertension lasted for 2 hours. During DKA treatment, the blood pressure was normal at baseline in 196 patients but progressed to hypertension during DKA treatment. Developed at any time during DKA, the resulting overall rate of hypertension was at 27.8 percent.

The median duration of  hypertension was 4.0 hours and at presentation, correlated with more severe acidosis and stage 2 or 3 acute kidney injury. On the contrary, at baseline, lower glucose levels or glucose-corrected sodium concentrations were associated with hypertension at presentation.

Lower scores on the Glasgow Coma Scale and more severe acidosis correlated with the development of hypertension at any point during DKA. Severe acidosis, stage 2 acute kidney injury, and younger patient age are also directly correlated with hypertension severity.

The researchers stated that a central mechanism may be involved in causing abnormal haemodynamic regulation with the development of hypertension during DKA treatment and the association of hypertension with altered mental status.

They also added that it is necessary to better understand relationships of regional cerebral blood flow abnormalities during DKA is necessary and how these relate to life-threatening cerebral injuries in some children.

Share the post!

Posted on

Erectile health in men gets affected by the functionality of their lungs

Cr. Tim Marshall

Source from MIMS.com

Based on recent study, erectile dysfunction (ED) appears to correlate with an impaired forced expiratory volume in 1 second (FEV1) out of other classic risk factors.

Free of a history of diabetes, cardiovascular or kidney diseases, 331 men were under supervision and assessment using the International Index of Erectile Function (IIEF-5) resulted into the main outcome of ED. Through mini-spirometry, FEV1 was measured under the guidance of a study nurse.

For normal predicted FEV1 values, sixty-six percent of the participants had it while 23 percent and 11 percent had mild and moderate impairments. Five patients had a history of chronic obstructive pulmonary disease (COPD), while four had a history of asthma with fifty-nine participants had moderate-to-severe ED.

A link between the impaired predicted FEV1 and moderate-to-severe ED were uncovered by researchers.

The risk of ED was increased by almost fivefold for men with FEV1, which is between 1.0-2.0 L/s. For those with predicted FEV1, the corresponding risk was over four times as high.

The researchers stated that the biological background can only be hypothesized since it is the first study to report the association between decreased pulmonary function and ED in apparently healthy men. Be that as it may, the findings underscore the importance of monitoring for sexual and erectile health in men with weak lung function.

Share the post!

Posted on

Early ageing of ovary: A future health problem?

Cr. Andre Piacquadio

Source from MIMS.com

A large cohort study that was presented at the 2020 ESHRE Meeting suggested that early ovarian ageing may be predictive of later health problems.

Few oocytes in Assisted Reproductive Technology (Art) were harvested from young women with premature ovarian ageing and were discovered to have a much higher risk of age-related diseases such as cardiovascular diseases (CVD) and osteoporosis compared to those with undergoing normal ovarian ageing and happens to be in line with what was known so far regarding early menopause.

Mette Wulf Christensen from Aarhus University in Denmark suggested that a few oocytes that were repeatedly harvested in well stimulated ART cycles is a likely predictor of advanced menopausal age when seen in young women and may thus serve as an early marker of accelerated general ageing. There is also an association shown between early menopause with a greater risk of CVD, osteoporosis, and death. She also said that identifying women at risk of early menopause may thus allow early preventive health initiatives in terms of  a healthy lifestyle.

The national cohort study that was based in Danish included >19,000 young women (≤37 years) who were undergoing their first ART treatment in a fertility clinic between the period of 1995-2014 with the number of oocytes harvested in the first and following cycles serves as a marker.

In a follow-up of 6 years span, women with early ovarian ageing for overall-disease risk has a higher risk than those with a normal oocyte field and they consisted of Alzheimer’s or Parkinson’s disease, all-cause death, cancer, cataract, Charlson Comorbidity index, CVD, early retirement benefit, osteoporosis and type 2 diabetes.

To be specific, the early ovarian ageing group was significantly more likely to develop osteoporosis, CVD, comorbidity, and have early retirement benefit than women with normal ovarian ageing.

Christhensen concluded that it is important to have a counselling towards the women who are affected with a much earlier menopause, with the introduction of a new lifestyle habit or  applying the use of hormone replacement therapy (HRT) to reduce the adverse health risks.

Share the post!

Posted on

Vaccines : Proven to be safe after a two decade study

Cr. CDC

Source from MIMS.com

There have been many doubts from naysayers who criticize the usage of vaccines as they claimed it could make their child get autistic and how it would make them get infected with the disease they are trying to prevent instead.

A recent US study that was conducted for over a 20-year period recently revealed that they have debunked the myths and shown that vaccines are relatively safe via existing postmarketing surveillance programmes, stated the authors.

The vaccines that were approved by the Food and Drug Administration (FDA) – the initial and subsequent labels – between 1 January 1996 and 31 December 2015 were included in the retrospective cohort study.

Out of the fifty-seven FDA-approved vaccines that were analysed, fifty-three (93 percent) initially had approval that were supported by randomized controlled trials, with a median cohort size of 4,161 participants.

There were similarities in the initial approval trial characteristics in vaccines with and without postmarketing, safety-related label modifications. The most common safety issue prompting label modifications was the expansion of population restrictions, followed by allergies with postmarketing surveillance as the most common source of safety data.

Share the post!

CONTACT US

Mon to Fri: 8:00am to 5:00pm
Sat: 8:30am to 12:30pm

QUICK LINKS

QUICK LINKS

© 2024 Mayflax

Facebook Linkedin Instagram