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Facing the pandemic with a mental health : Students are struggling

Cr. Sam Balye

Source from WebMD.com

College life could be both stressful and demanding and from that, anxiety, depression and inactive lifestyles are actually common among students. Now with the pandemic of COVID-19 happening worldwide, a new study might have found that the mental-health issues could be escalated and turn for the worst.

Researchers at Dartmouth College determined that the coronavirus pandemic had an immediate impact on the mental health of this particular undergraduate group of 200 students, using a mix of smartphone data and online surveys.

The study involved students who were participating in a research program tracking mental health at the New Hampshire university with Spikes of depression and anxiety were reported at the beginning of the pandemic in early March, just as the school pushed students to leave campus and begin remote learning all by their selves.

The study found out that the students’ overall anxiety and depression levels remained consistently high than in previous years, even if their self-reported anxiety and depression lessened slightly later on in the semester.

Jeremy Huckins, a lecturer at Dartmouth stated that there is a large-scale shift in mental health and behaviour compared to the observed baseline established for the group over previous years.

In addition, the students reported around spring break period in mid-March that their day-to-day lives were dramatically more sedentary than pervious terms.

Huckins suspected that spring break 2020 was stressful and confining for the students in the study and it might be responsible for a large number of college students across the country even though it is usually a period of decreased stress and increased physical activity.

A smartphone app developed at Dartmouth was used by the researchers to calculate sedentary time. It collected information such as number of phone unlocks, phone usage duration and sleep duration from the student volunteers.

Through the app, data on depression and anxiety were also collected using weekly, self-reported questionnaires. The decrease in activity among these students may have been related to lockdown orders implemented at the time.

Huckins also said that when social distancing was recommended by local governments, students were more sedentary and visited fewer locations on any given day. “The impact of COVID-19 extends beyond the virus and its direct impacts. An unresolved question is if mental health and physical activity will continue to degrade over time, or if we will see a recovery, and how long that recovery will take”.

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Diabetic ketoacidosis in children equals to hypertension

Cr. Rene Bernal

Source from MIMS.com

Study has found that for children with diabetic ketoacidosis (DKA), hypertension is a common phenomenon.

Researchers gathered 1,258 patients who had sufficient haemodynamic data for the present analysis while using data from the Paediatric Emergency Care Applied Research Network. Out of these, 12.2 percent had documented hypertension at presentation.

In under 2 hours, hypertension were resolved quickly in 36 children and for 118 episodes, hypertension lasted for 2 hours. During DKA treatment, the blood pressure was normal at baseline in 196 patients but progressed to hypertension during DKA treatment. Developed at any time during DKA, the resulting overall rate of hypertension was at 27.8 percent.

The median duration of  hypertension was 4.0 hours and at presentation, correlated with more severe acidosis and stage 2 or 3 acute kidney injury. On the contrary, at baseline, lower glucose levels or glucose-corrected sodium concentrations were associated with hypertension at presentation.

Lower scores on the Glasgow Coma Scale and more severe acidosis correlated with the development of hypertension at any point during DKA. Severe acidosis, stage 2 acute kidney injury, and younger patient age are also directly correlated with hypertension severity.

The researchers stated that a central mechanism may be involved in causing abnormal haemodynamic regulation with the development of hypertension during DKA treatment and the association of hypertension with altered mental status.

They also added that it is necessary to better understand relationships of regional cerebral blood flow abnormalities during DKA is necessary and how these relate to life-threatening cerebral injuries in some children.

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Vaccines : Proven to be safe after a two decade study

Cr. CDC

Source from MIMS.com

There have been many doubts from naysayers who criticize the usage of vaccines as they claimed it could make their child get autistic and how it would make them get infected with the disease they are trying to prevent instead.

A recent US study that was conducted for over a 20-year period recently revealed that they have debunked the myths and shown that vaccines are relatively safe via existing postmarketing surveillance programmes, stated the authors.

The vaccines that were approved by the Food and Drug Administration (FDA) – the initial and subsequent labels – between 1 January 1996 and 31 December 2015 were included in the retrospective cohort study.

Out of the fifty-seven FDA-approved vaccines that were analysed, fifty-three (93 percent) initially had approval that were supported by randomized controlled trials, with a median cohort size of 4,161 participants.

There were similarities in the initial approval trial characteristics in vaccines with and without postmarketing, safety-related label modifications. The most common safety issue prompting label modifications was the expansion of population restrictions, followed by allergies with postmarketing surveillance as the most common source of safety data.

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